SCHEMBL31489444

SCHEMBL31489444

COC(=O)C(c1ccc(F)cc1)n1cc(B2OC(C)(C)C(C)(C)O2)cn1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
FFAR1 O14842 1/20 0.39
CXCR2 P25025 3/20 0.36
DGAT1 O75907 1/20 0.35
NR3C2 P08235 1/20 0.35
ELANE P08246 1/20 0.34
MDM2 Q00987 5/20 0.33
UCHL1 P09936 1/20 0.33
F2 P00734 1/20 0.33
F10 P00742 1/20 0.33
F11 P03951 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23303904 0.89 KMT2A (0.41) LPLLIPGFFAR1DGAT1NR3C2
SCHEMBL15653015 0.79 LPL (0.47) LPLLIPGFFAR1CXCR2
SCHEMBL3663499 0.79 FFAR1 (0.45) FFAR1DGAT1UCHL1
SCHEMBL31489511 0.79 LPL (0.47) LPLLIPGFFAR1CXCR2
SCHEMBL11931387 0.78 FFAR1 (0.41) LPLLIPGFFAR1DGAT1UCHL1
SCHEMBL16784496 0.77 FFAR1 (0.43) LPLLIPGFFAR1DGAT1F2
SCHEMBL22558697 0.77 LPL (0.44) LPLLIPGFFAR1CXCR2
SCHEMBL31489464 0.76 LPL (0.42) LPLLIPGFFAR1CXCR2
SCHEMBL14542888 0.76 FFAR1 (0.42) LPLLIPGFFAR1DGAT1F2
SCHEMBL22585809 0.76 LPL (0.43) LPLLIPGFFAR1CXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed