Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489849 | 0.83 | CYP17A1 (0.39) | ITK | |
| SCHEMBL69872 | 0.81 | KCNN4 (0.36) | — | |
| SCHEMBL14699376 | 0.79 | ITK (0.41) | ITKCYP2B6TAAR1MAPK1ALDH1A1 | |
| SCHEMBL14699125 | 0.72 | F2 (0.48) | ITKALDH1A1 | |
| SCHEMBL31010345 | 0.71 | FFAR1 (0.30) | — | |
| SCHEMBL20899324 | 0.70 | LMNA (0.43) | — | |
| SCHEMBL22513035 | 0.67 | — | — | |
| SCHEMBL20899261 | 0.67 | LRRK2 (0.36) | — | |
| SCHEMBL22531269 | 0.67 | PDK2 (0.39) | — | |
| SCHEMBL21791747 | 0.67 | LRRK2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |