Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 10/20 | 0.45 |
| ▸ | CLK1 | P49759 | 5/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489790 | 1.00 | CREBBP (0.45) | CREBBPCLK1DYRK1AGPR55JAK2 | |
| SCHEMBL31489417 | 0.79 | CREBBP (0.46) | CREBBPCLK1DYRK1AGPR55JAK2 | |
| SCHEMBL31489474 | 0.79 | CREBBP (0.46) | CREBBPCLK1DYRK1AGPR55JAK2 | |
| SCHEMBL31489380 | 0.75 | CREBBP (0.40) | CREBBPCLK1DYRK1AGPR55JAK2 | |
| SCHEMBL31489470 | 0.75 | CREBBP (0.40) | CREBBPCLK1DYRK1AGPR55JAK2 | |
| SCHEMBL31489347 | 0.75 | CREBBP (0.42) | CREBBPGPR55CYP17A1 | |
| SCHEMBL31489263 | 0.75 | CREBBP (0.46) | CREBBPCLK1DYRK1AGPR55CYP17A1 | |
| SCHEMBL31489258 | 0.75 | CREBBP (0.42) | CREBBPGPR55CYP17A1 | |
| SCHEMBL31489687 | 0.74 | CREBBP (0.43) | CREBBPCLK1DYRK1AGPR55JAK2 | |
| SCHEMBL31489560 | 0.74 | CREBBP (0.43) | CREBBPCLK1DYRK1AGPR55JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |