SCHEMBL31489263

SCHEMBL31489263

CC(c1ccc(F)cc1)n1cc(-c2cc(F)cc(Br)c2F)cn1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 11/20 0.46
BRD4 O60885 4/20 0.38
MET P08581 3/20 0.37
GPR55 Q9Y2T6 1/20 0.36
NTRK1 P04629 1/20 0.35
CLK1 P49759 1/20 0.34
DYRK1A Q13627 1/20 0.34
CYP17A1 P05093 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489843 0.90 CREBBP (0.43) CREBBPBRD4NTRK1
SCHEMBL31489519 0.85 CREBBP (0.46) CREBBPBRD4GPR55CYP17A1
SCHEMBL31489202 0.85 CREBBP (0.46) CREBBPBRD4GPR55CYP17A1
SCHEMBL31489417 0.76 CREBBP (0.46) CREBBPGPR55CLK1DYRK1ACYP17A1
SCHEMBL31489474 0.76 CREBBP (0.46) CREBBPGPR55CLK1DYRK1ACYP17A1
SCHEMBL31489706 0.75 CREBBP (0.43) CREBBPBRD4GPR55CLK1DYRK1A
SCHEMBL31489680 0.75 CREBBP (0.43) CREBBPBRD4GPR55CLK1DYRK1A
SCHEMBL31489452 0.75 CREBBP (0.45) CREBBPGPR55CLK1DYRK1ACYP17A1
SCHEMBL31489790 0.75 CREBBP (0.45) CREBBPGPR55CLK1DYRK1ACYP17A1
SCHEMBL31489560 0.74 CREBBP (0.43) CREBBPBRD4GPR55CLK1DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed