Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 7/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489504 | 0.84 | CREBBP (0.44) | PIK3CGPIK3CDPDK2FEN1 | |
| SCHEMBL31489737 | 0.82 | RIPK1 (0.38) | PIK3CGPIK3CDPDK2RIPK1FEN1 | |
| SCHEMBL31489509 | 0.82 | RIPK1 (0.38) | PIK3CGPIK3CDPDK2RIPK1FEN1 | |
| SCHEMBL31489250 | 0.81 | PDK2 (0.35) | PDK2JAK2 | |
| SCHEMBL31480922 | 0.77 | PIK3CG (0.47) | PIK3CGPIK3CDPDK2RIPK1 | |
| SCHEMBL31489369 | 0.76 | RIPK1 (0.39) | PIK3CGPIK3CDPDK2RIPK1FEN1 | |
| SCHEMBL31489934 | 0.76 | RIPK1 (0.39) | PIK3CGPIK3CDPDK2RIPK1FEN1 | |
| SCHEMBL25439967 | 0.75 | RIPK1 (0.42) | PIK3CGPIK3CDRIPK1TDP2JAK2 | |
| SCHEMBL31489893 | 0.75 | PDK2 (0.45) | PDK2SRCGRIN2B | |
| SCHEMBL29498052 | 0.75 | RIPK1 (0.42) | PIK3CGPIK3CDRIPK1TDP2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |