Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | GLA | P06280 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544142 | 0.75 | JAK2 (0.50) | JAK2JAK3CYP11B2PDE10AKDM4E | |
| SCHEMBL31489689 | 0.75 | AHR (0.50) | PDE10AKDM4EALDH1A1NPC1HTT | |
| SCHEMBL31489671 | 0.71 | CA1 (0.32) | KDM4E | |
| SCHEMBL31489938 | 0.71 | PDE10A (0.41) | JAK2PDE10AKDM4EALDH1A1GAA | |
| SCHEMBL15827807 | 0.71 | JAK2 (0.50) | JAK2JAK3CYP11B2PDE10AKDM4E | |
| SCHEMBL10271750 | 0.70 | JAK2 (0.46) | JAK2JAK3CYP11B2PDE10AKDM4E | |
| SCHEMBL31489179 | 0.69 | KDM4E (0.35) | JAK2PDE10AKDM4EALDH1A1NPC1 | |
| SCHEMBL27330270 | 0.68 | JAK2 (0.36) | JAK2JAK3CYP11B2PDE10AKDM4E | |
| SCHEMBL21162487 | 0.68 | PRKDC (0.47) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL18911313 | 0.68 | PDE10A (0.49) | JAK2JAK3CYP11B2PDE10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |