Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489910 | 0.84 | CYP11B2 (0.37) | KDM4EALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL31489399 | 0.82 | KDM4E (0.35) | KDM4EALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL31489506 | 0.80 | ROCK2 (0.34) | KDM4EALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL31489376 | 0.78 | TDP2 (0.32) | PDE10ATDP2 | |
| SCHEMBL31489371 | 0.73 | PDE10A (0.37) | KDM4EMAPK1PDE10A | |
| SCHEMBL31489503 | 0.71 | PDE10A (0.34) | PDE10ATDP2 | |
| SCHEMBL31489689 | 0.71 | AHR (0.50) | KDM4EALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL31489476 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1JAK2 | |
| SCHEMBL31489600 | 0.69 | JAK2 (0.44) | KDM4EALDH1A1HTTPDE10AJAK2 | |
| SCHEMBL31489671 | 0.68 | CA1 (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |