Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 9/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.32 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489556 | 1.00 | RIPK1 (0.40) | RIPK1TDP2PIK3CGPIK3CDBRAF | |
| SCHEMBL31489774 | 0.91 | RIPK1 (0.41) | RIPK1TDP2PIK3CGPIK3CDPAK4 | |
| SCHEMBL31489421 | 0.91 | RIPK1 (0.41) | RIPK1TDP2PIK3CGPIK3CDPAK4 | |
| SCHEMBL31489253 | 0.90 | RIPK1 (0.40) | RIPK1TDP2PIK3CGPIK3CDPAK4 | |
| SCHEMBL31489633 | 0.86 | RIPK1 (0.40) | RIPK1PIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31489701 | 0.86 | RIPK1 (0.40) | RIPK1PIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31489887 | 0.83 | RIPK1 (0.42) | RIPK1TDP2PIK3CGPIK3CDPAK4 | |
| SCHEMBL31489651 | 0.83 | RIPK1 (0.41) | RIPK1PIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31489662 | 0.82 | RIPK1 (0.42) | RIPK1PIK3CGPIK3CDPAK4JAK1 | |
| SCHEMBL31489458 | 0.82 | RIPK1 (0.42) | RIPK1PIK3CGPIK3CDPAK4JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |