Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489826 | 1.00 | RIPK1 (0.36) | RIPK1PIK3CAPIK3CGPIK3CDROCK2 | |
| SCHEMBL31489856 | 0.88 | MKNK1 (0.34) | RIPK1PIK3CAPIK3CGPIK3CDROCK2 | |
| SCHEMBL31489584 | 0.88 | MKNK1 (0.34) | RIPK1PIK3CAPIK3CGPIK3CDROCK2 | |
| SCHEMBL31489468 | 0.85 | CREBBP (0.33) | RIPK1ROCK2CREBBPKIT | |
| SCHEMBL31489700 | 0.85 | CREBBP (0.33) | RIPK1ROCK2CREBBPKIT | |
| SCHEMBL31489795 | 0.85 | RIPK1 (0.34) | RIPK1ROCK2 | |
| SCHEMBL31489398 | 0.85 | RIPK1 (0.34) | RIPK1ROCK2 | |
| SCHEMBL31489724 | 0.85 | RIPK1 (0.35) | RIPK1ROCK2CREBBPKIT | |
| SCHEMBL31489821 | 0.85 | RIPK1 (0.35) | RIPK1ROCK2CREBBPKIT | |
| SCHEMBL31489201 | 0.84 | RIPK1 (0.35) | RIPK1PIK3CAPIK3CGROCK2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |