Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.33 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489908 | 1.00 | RIPK1 (0.37) | RIPK1PIK3CGPIK3CDCYP17A1JAK1 | |
| SCHEMBL31489759 | 0.94 | RIPK1 (0.38) | RIPK1PIK3CGPIK3CDJAK1PAK4 | |
| SCHEMBL31489414 | 0.94 | RIPK1 (0.38) | RIPK1PIK3CGPIK3CDJAK1PAK4 | |
| SCHEMBL31489633 | 0.88 | RIPK1 (0.40) | RIPK1PIK3CGPIK3CDJAK1PAK4 | |
| SCHEMBL31489701 | 0.88 | RIPK1 (0.40) | RIPK1PIK3CGPIK3CDJAK1PAK4 | |
| SCHEMBL31489761 | 0.87 | JAK2 (0.33) | PIK3CGPIK3CDCYP17A1JAK1PIK3CA | |
| SCHEMBL31489367 | 0.86 | PIK3CG (0.37) | RIPK1PIK3CGPIK3CDCYP17A1JAK1 | |
| SCHEMBL31489786 | 0.86 | PIK3CG (0.37) | RIPK1PIK3CGPIK3CDCYP17A1JAK1 | |
| SCHEMBL31489337 | 0.86 | JAK2 (0.32) | PIK3CGPIK3CDCYP17A1JAK1PIK3CA | |
| SCHEMBL31489876 | 0.85 | PIK3CG (0.39) | RIPK1PIK3CGPIK3CDCYP17A1JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |