SCHEMBL31489655

SCHEMBL31489655

CCC(c1ccc(F)cc1)n1cc(-c2cncc(-c3ccn4nc(-n5c(C)ccc5C)nc4c3OC)n2)cn1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.32
PIK3CA P42336 1/20 0.32
PIK3CG P48736 1/20 0.32
CYP17A1 P05093 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489684 0.92 PIK3CD (0.34) PIK3CDPIK3CAPIK3CG
SCHEMBL31489446 0.91 CYP17A1 (0.32) CYP17A1
SCHEMBL31489585 0.87 PIK3CD (0.35) PIK3CDPIK3CAPIK3CGCYP17A1
SCHEMBL31489146 0.83 JAK2 (0.33) PIK3CDPIK3CAPIK3CGCYP17A1
SCHEMBL31489133 0.83 JAK2 (0.33) PIK3CDPIK3CAPIK3CGCYP17A1
SCHEMBL31489378 0.82 PIK3CD (0.35) PIK3CDPIK3CAPIK3CG
SCHEMBL31489714 0.82 CYP17A1 (0.32) CYP17A1
SCHEMBL31489715 0.82 CYP17A1 (0.32) CYP17A1
SCHEMBL31489881 0.79 PIK3CD (0.37) PIK3CDPIK3CAPIK3CGCYP17A1
SCHEMBL31489785 0.79 CYP17A1 (0.34) PIK3CDPIK3CAPIK3CGCYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed