Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489715 | 1.00 | CYP17A1 (0.32) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489341 | 0.92 | JAK2 (0.33) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489446 | 0.88 | CYP17A1 (0.32) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489231 | 0.87 | CYP17A1 (0.34) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489323 | 0.87 | — | — | |
| SCHEMBL31489776 | 0.87 | — | — | |
| SCHEMBL31489146 | 0.82 | JAK2 (0.33) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489655 | 0.82 | PIK3CD (0.32) | CYP17A1 | |
| SCHEMBL31489484 | 0.81 | — | — | |
| SCHEMBL31489614 | 0.79 | JAK2 (0.34) | CYP17A1JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |