Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 7/20 | 0.44 |
| ▸ | AKT2 | P31751 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | ILK | Q13418 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861348 | 0.77 | AKT1 (0.44) | AKT1AKT2MAPK1ILKCD38 | |
| SCHEMBL13097161 | 0.77 | AKT1 (0.44) | AKT1AKT2MAPK1CYP11B2CYP11B1 | |
| SCHEMBL21193202 | 0.74 | CYP11B2 (0.46) | AKT1AKT2MAPK1CYP11B2CYP11B1 | |
| SCHEMBL6196346 | 0.74 | — | — | |
| SCHEMBL1365945 | 0.74 | AKT1 (0.48) | AKT1AKT2MAPK1ILKPRKD3 | |
| SCHEMBL3740850 | 0.73 | AKT2 (0.70) | AKT1AKT2MAPK1ILK | |
| SCHEMBL13086435 | 0.73 | MAPK8 (0.43) | AKT1AKT2MAPK1ILKCD38 | |
| Hydrochloric Acid SCHEMBL28973063 | 0.71 | AKT2 (0.67) | AKT1AKT2MAPK1ILK | |
| SCHEMBL15574039 | 0.71 | AKT2 (0.50) | AKT1AKT2MAPK1ILKMAPT | |
| SCHEMBL14941606 | 0.71 | PIK3CD (0.52) | AKT1AKT2MAPK1PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |