Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 9/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489479 | 1.00 | CREBBP (0.52) | CREBBPHDAC8CYP3A4CYP2C19LMNA | |
| SCHEMBL31489905 | 0.84 | CREBBP (0.51) | CREBBPLMNABRD4ALDH1A1NPSR1 | |
| SCHEMBL31489764 | 0.84 | CREBBP (0.51) | CREBBPLMNABRD4ALDH1A1NPSR1 | |
| SCHEMBL23022268 | 0.83 | CREBBP (0.56) | CREBBPLMNAGAASLC6A2SLC6A4 | |
| SCHEMBL31489224 | 0.81 | CREBBP (0.39) | CREBBPDYRK1A | |
| SCHEMBL31489591 | 0.81 | CREBBP (0.39) | CREBBPDYRK1A | |
| SCHEMBL31489672 | 0.81 | PDE2A (0.37) | CREBBP | |
| SCHEMBL31489456 | 0.81 | PDE2A (0.37) | CREBBP | |
| SCHEMBL15564195 | 0.79 | CREBBP (0.52) | CREBBPCYP3A4CYP2C19LMNARECQL | |
| SCHEMBL31489420 | 0.78 | CREBBP (0.56) | CREBBPCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |