Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 10/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489456 | 1.00 | PDE2A (0.37) | PDE2ACREBBPTEAD1PDE9ACES2 | |
| SCHEMBL31489591 | 0.83 | CREBBP (0.39) | CREBBP | |
| SCHEMBL31489224 | 0.83 | CREBBP (0.39) | CREBBP | |
| SCHEMBL31489752 | 0.81 | CREBBP (0.52) | CREBBP | |
| SCHEMBL31489479 | 0.81 | CREBBP (0.52) | CREBBP | |
| SCHEMBL23212733 | 0.79 | CYP2B6 (0.48) | PDE2ACES2 | |
| SCHEMBL29871073 | 0.79 | CYP2B6 (0.48) | PDE2ACES2 | |
| SCHEMBL31489764 | 0.79 | CREBBP (0.51) | CREBBP | |
| SCHEMBL31489905 | 0.79 | CREBBP (0.51) | CREBBP | |
| SCHEMBL24208620 | 0.77 | ACHE (0.47) | CREBBPTEAD1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |