Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 7/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489910 | 0.75 | CYP11B2 (0.37) | CYP11B2CYP11B1PIK3CBPIK3CGPIK3CD | |
| SCHEMBL31489173 | 0.74 | CYP11B1 (0.31) | CYP11B2CYP11B1PIK3CBPIK3CGPIK3CD | |
| SCHEMBL31489569 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL31489321 | 0.72 | KDM4E (0.40) | CYP11B2 | |
| SCHEMBL31489274 | 0.70 | — | — | |
| SCHEMBL31403018 | 0.66 | CYP11B2 (0.69) | CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL31489938 | 0.65 | PDE10A (0.41) | ALDH1A1 | |
| SCHEMBL31489331 | 0.65 | KDM4E (0.37) | — | |
| SCHEMBL31489562 | 0.65 | KDM4E (0.37) | — | |
| SCHEMBL16747922 | 0.62 | CYP11B2 (0.39) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |