SCHEMBL31489784

SCHEMBL31489784

Cc1nn(C(c2ccc(F)cc2)C(C)(F)F)cc1-c1cncc(-c2ccn3nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc3c2)n1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489896 1.00 RIPK1 (0.30) RIPK1
SCHEMBL31489859 0.89 RIPK1 (0.31) RIPK1
SCHEMBL31489416 0.89 RIPK1 (0.31) RIPK1
SCHEMBL31489288 0.88 RIPK1 (0.31) RIPK1
SCHEMBL31489612 0.85 RIPK1 (0.30) RIPK1
SCHEMBL31489810 0.85 RIPK1 (0.30) RIPK1
SCHEMBL31489627 0.85 RIPK1 (0.31) RIPK1
SCHEMBL31489617 0.85 RIPK1 (0.31) RIPK1
SCHEMBL31489572 0.83 PIK3CG (0.34) RIPK1
SCHEMBL31489187 0.82 PIK3CG (0.42) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed