SCHEMBL31489846

SCHEMBL31489846

CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1CCN

nearest known ligand 0.86

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.76
PGR P06401 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL22656804 0.99 AR (0.74) ARPGR
SCHEMBL8704575 0.92 AR (0.77) ARPGR
SCHEMBL7783753 0.90 AR (0.77) ARPGR
SCHEMBL633929 0.90 AR (0.88) ARPGR
SCHEMBL8516863 0.89 AR (0.79) AR
SCHEMBL4025147 0.89 AR (0.76) ARPGR
SCHEMBL4028572 0.89 AR (0.86) ARPGR
SCHEMBL4025060 0.89 AR (0.76) ARPGR
Hydrochloric Acid SCHEMBL22656831 0.89 AR (0.77) AR
SCHEMBL4027208 0.88 AR (0.74) ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798228-A PROTAC compound for targeted degradation of AR/AR-V7 and preparation method and application thereof 常州大学 2025-04-11 CN disclosed