SCHEMBL7783753

SCHEMBL7783753

CCCN1C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)C1(C)C

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.77
PGR P06401 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8704575 0.91 AR (0.77) ARPGR
SCHEMBL633929 0.91 AR (0.88) ARPGR
SCHEMBL4027208 0.91 AR (0.74) ARPGR
SCHEMBL4028572 0.90 AR (0.86) ARPGR
SCHEMBL4025060 0.90 AR (0.76) ARPGR
SCHEMBL4025147 0.90 AR (0.76) ARPGR
SCHEMBL31489846 0.90 AR (0.76) ARPGR
Hydrochloric Acid SCHEMBL22656804 0.89 AR (0.74) ARPGR
SCHEMBL4024956 0.89 AR (0.77) AR
SCHEMBL7781110 0.88 AR (0.80) ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671156-B1 Process to prepare cosmetic or pharmaceutical compositions containing liposomes AVENTIS PHARMA SA (FR) 2001-10-24 EP disclosed
US-6162444-A Cosmetic or pharmaceutical compositions HOECHST MARION ROUSSEL (FR) 2000-12-19 US disclosed
US-RE35956-E Phenylimidazolidines having antiandrogenic activity ROUSSEL UCLAF (FR) 1998-11-10 US disclosed
US-5627201-A Phenylimidazolidines having antiandrogenic activity ROUSSEL UCLAF (FR) 1997-05-06 US disclosed
EP-0494819-B1 Phenylimidazolidines, their process for fabrication, their application as medicaments and the pharmaceutical compositions containing them ROUSSEL UCLAF (FR) 1996-07-10 EP disclosed
EP-0671156-A1 Cosmetic or pharmaceutical compositions containing liposomes ROUSSEL UCLAF (FR) 1995-09-13 EP disclosed
US-5411981-A Phenylimidazolidines having antiandrogenic activity ROUSSEL UCLAF (FR) 1995-05-02 US disclosed
EP-0494819-A1 Phenylimidazolidines, their process for fabrication, their application as medicaments and the pharmaceutical compositions containing them ROUSSEL UCLAF (FR) 1992-07-15 EP disclosed