SCHEMBL31489883

SCHEMBL31489883

Fc1c(Br)ccc(Cl)c1I

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.31
KCNH2 Q12809 2/20 0.31
KDM1B Q8NB78 2/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22289556 1.00 KDM1A (0.31) KDM1AKCNH2KDM1BNOTUM
SCHEMBL23403883 0.81 NOTUM (0.30) NOTUM
SCHEMBL31251851 0.81 NOTUM (0.30) NOTUM
SCHEMBL31342136 0.77 KDM1A (0.39) KDM1AKCNH2KDM1B
SCHEMBL2014602 0.77 KDM1A (0.39) KDM1AKCNH2KDM1B
SCHEMBL2013956 0.75 CYP3A4 (0.35) KDM1AKCNH2KDM1B
SCHEMBL31070219 0.75 CYP3A4 (0.35) KDM1AKCNH2KDM1B
SCHEMBL16618074 0.75 KDM1A (0.33) KDM1AKCNH2KDM1B
SCHEMBL17711300 0.73 NOTUM (0.40) KDM1AKCNH2KDM1BNOTUM
SCHEMBL30384989 0.73 NOTUM (0.40) KDM1AKCNH2KDM1BNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed