SCHEMBL31490293

SCHEMBL31490293

CCc1cnc2c(CCl)c(Cl)ccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.43
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34
MCHR1 Q99705 2/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
KCNH2 Q12809 1/20 0.32
HRH4 Q9H3N8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
SLC22A12 Q96S37 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA6 P23280 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10706774 0.81 PARP1 (0.46) PARP1CCR1CCR5CCR8MCHR1
SCHEMBL31490370 0.81 PARP1 (0.46) PARP1CCR1CCR5CCR8MCHR1
SCHEMBL31490366 0.81 CCR1 (0.58) PARP1CCR1CCR5CCR8CYP1A2
SCHEMBL10836786 0.80 CCR1 (0.34) CCR1CCR5CCR8ALKSMN1; SMN2
SCHEMBL20042363 0.79 PARP1 (0.56) PARP1CCR1CCR5CCR8CYP1A2
SCHEMBL13990811 0.76 CCR1 (0.37) PARP1CCR1CCR5CCR8SLC22A12
SCHEMBL9346616 0.76 PARP1 (0.57) PARP1CCR1CCR5CCR8MCHR1
SCHEMBL31490355 0.75 ALK (0.56) PARP1PDE4APDE4BPDE4CPDE4D
SCHEMBL10344237 0.75 ALK (0.56) PARP1PDE4APDE4BPDE4CPDE4D
SCHEMBL10344238 0.72 PARP1 (0.47) PARP1PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119859121-A Preparation method of quinic acid compound 北京颖泰嘉和生物科技股份有限公司 2025-04-22 CN disclosed