Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560933 | 1.00 | NPC1 (0.47) | NPC1RAB9APOLBNPSR1GALR3 | |
| SCHEMBL4027384 | 0.87 | GALR3 (0.46) | NPC1RAB9APOLBNPSR1GALR3 | |
| SCHEMBL5758834 | 0.87 | ELANE (0.55) | NPC1RAB9APOLBNPSR1GALR3 | |
| SCHEMBL5434834 | 0.85 | GALR3 (0.46) | NPC1RAB9APOLBNPSR1GALR3 | |
| SCHEMBL31490157 | 0.82 | ELANE (0.49) | ELANECCR1NOTUM | |
| SCHEMBL561776 | 0.82 | ELANE (0.49) | ELANECCR1NOTUM | |
| SCHEMBL561541 | 0.80 | ELANE (0.47) | ELANECCR1 | |
| SCHEMBL31490320 | 0.80 | ELANE (0.47) | ELANECCR1 | |
| SCHEMBL561729 | 0.79 | CHRNB2 (0.55) | ELANECCR1NOTUM | |
| SCHEMBL31490135 | 0.79 | PPARG (0.51) | POLBKDM4EELANEALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056602-A1 | PHARMACEUTICAL COMPOSITIONS AND USE THEREOF IN TREATMENT OF CONDITIONS AND DISEASES RELATED TO ELASTIN DEFICIENCY AND/OR AGING | Elastin Biosciences Ltd. (GB) | 2025-03-20 | — | — | WO | disclosed |