SCHEMBL31490975

SCHEMBL31490975

O=C(Nc1ccc(OC(F)(F)F)cc1)C(F)(F)Br

nearest known ligand 0.73

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.73
MAPT P10636 2/20 0.62
TRPV1 Q8NER1 3/20 0.59
KMT2A Q03164 1/20 0.59
FAAH O00519 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
KDM4E B2RXH2 1/20 0.56
HPGD P15428 1/20 0.55
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
EPHX1 P07099 2/20 0.54
LMNA P02545 1/20 0.51
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11555827 0.85 EPHX2 (1.00) EPHX2MAPTTRPV1KMT2AFAAH
SCHEMBL31490980 0.84 PDK1 (0.69) EPHX2MAPTKMT2AL3MBTL1KDM4E
SCHEMBL3022084 0.84 EPHX2 (0.71) EPHX2MAPTTRPV1KMT2AFAAH
SCHEMBL2096310 0.83 EPHX2 (0.76) EPHX2MAPTTRPV1KMT2AFAAH
SCHEMBL2096312 0.83 EPHX2 (0.76) EPHX2MAPTTRPV1KMT2AFAAH
SCHEMBL169453 0.81 EPHX2 (0.73) EPHX2MAPTTRPV1KMT2AFAAH
SCHEMBL9070653 0.81 EPHX2 (0.73) EPHX2MAPTTRPV1KMT2AFAAH
SCHEMBL8966042 0.81 EPHX2 (0.73) EPHX2MAPTTRPV1KMT2AFAAH
SCHEMBL28286765 0.81 EPHX2 (0.73) EPHX2MAPTTRPV1KMT2AFAAH
SCHEMBL31499794 0.81 EPHX2 (0.67) EPHX2MAPTTRPV1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823137-A Nitrogen-containing cyclopyranoside derivative and preparation method thereof 淮北师范大学 2025-04-15 CN disclosed