Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785588 | 0.94 | PDE4B (0.49) | PDE4BPDE4DMAPTSMN1; SMN2HTT | |
| SCHEMBL23586242 | 0.84 | PDE4B (0.65) | PDE4BPDE4D | |
| SCHEMBL31572380 | 0.84 | PDE4B (0.44) | PDE4BPDE4DMAPTSMN1; SMN2POLB | |
| SCHEMBL30785554 | 0.80 | PDE4B (0.56) | PDE4BPDE4D | |
| SCHEMBL31572366 | 0.78 | PDE4B (0.51) | PDE4BPDE4DMAPTMEN1KMT2A | |
| SCHEMBL30785597 | 0.77 | MAPT (0.43) | MAPTSMN1; SMN2HTTKDM4EPOLB | |
| SCHEMBL31572368 | 0.76 | PDE4B (0.50) | PDE4BPDE4DMAPTMEN1KMT2A | |
| SCHEMBL31572403 | 0.76 | PDE4B (0.43) | PDE4BPDE4D | |
| SCHEMBL31469083 | 0.74 | PDE4B (0.47) | PDE4BPDE4D | |
| SCHEMBL17055090 | 0.73 | MAPT (0.47) | PDE4BMAPTSMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067168-A1 | AZA FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州爱科百发生物医药技术有限公司 | 2025-04-03 | — | — | WO | disclosed |