Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 15/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31572388 | 0.89 | PDE4B (0.44) | PDE4BPDE4DSYK | |
| SCHEMBL31571896 | 0.83 | PDE4B (0.48) | PDE4BPDE4D | |
| SCHEMBL31572380 | 0.79 | PDE4B (0.44) | PDE4BPDE4DSYK | |
| SCHEMBL31572368 | 0.77 | PDE4B (0.50) | PDE4BPDE4D | |
| SCHEMBL31491322 | 0.76 | PDE4B (0.57) | PDE4BPDE4D | |
| SCHEMBL7906240 | 0.74 | MEN1 (0.42) | PDE4BPDE4DDHODH | |
| SCHEMBL31572377 | 0.72 | PDE4B (0.44) | PDE4BPDE4D | |
| SCHEMBL31572366 | 0.72 | PDE4B (0.51) | PDE4BPDE4D | |
| SCHEMBL30785588 | 0.70 | PDE4B (0.49) | PDE4BPDE4D | |
| SCHEMBL1769552 | 0.67 | OPRM1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025092985-A1 | PHOSPHODIESTERASE 4B INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 合肥医工医药股份有限公司 | 2025-05-08 | — | — | WO | disclosed |