Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL55207 | 0.90 | ALOX15 (0.59) | — | |
| Acetic Acid SCHEMBL7132795 | 0.90 | FFAR3 (0.47) | — | |
| Acetic Acid SCHEMBL6449854 | 0.90 | FFAR3 (0.47) | — | |
| Acetic Acid SCHEMBL4492710 | 0.90 | — | — | |
| Acetic Acid SCHEMBL3891856 | 0.87 | — | — | |
| Succinic Acid SCHEMBL2126097 | 0.84 | PHF8 (0.55) | — | |
| Maleic Acid SCHEMBL28379898 | 0.82 | TSHR (0.50) | — | |
| SCHEMBL55546 | 0.80 | — | — | |
| Adipic Acid SCHEMBL7092451 | 0.80 | AKR1B1 (0.59) | — | |
| Acrylic Acid SCHEMBL17458929 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025046420-A1 | COMPOUND TARGETING EGR-1 AND USE THEREOF FOR TREATMENT OF ATOPIC DERMATITIS | 주식회사 아제라메디 | 2025-03-06 | — | — | WO | claimed |
| WO-2025046420-A1 | COMPOUND TARGETING EGR-1 AND USE THEREOF FOR TREATMENT OF ATOPIC DERMATITIS | 주식회사 아제라메디 | 2025-03-06 | — | — | WO | disclosed |