Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 14/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14828842 | 0.76 | TP53 (0.55) | PARP1TP53AURKBCHEK1CDC7 | |
| SCHEMBL29893472 | 0.76 | PARP1 (0.47) | PARP1TP53CHEK1TYRO3NAMPT | |
| SCHEMBL30809704 | 0.73 | PARP1 (0.65) | PARP1TP53DAOCDC7PLK4 | |
| SCHEMBL24098812 | 0.73 | PARP1 (0.65) | PARP1TP53DAOCDC7PLK4 | |
| SCHEMBL8566784 | 0.71 | PARP1 (0.49) | PARP1TP53DAOAURKA | |
| SCHEMBL29892776 | 0.70 | PARP1 (0.41) | PARP1TP53AURKBPRKD3MAP4K4 | |
| SCHEMBL9106684 | 0.70 | PARP1 (0.65) | PARP1TP53AURKBDAOCDC7 | |
| SCHEMBL30363017 | 0.70 | PARP1 (0.65) | PARP1TP53AURKBDAOCDC7 | |
| SCHEMBL29893693 | 0.70 | TP53 (0.55) | PARP1TP53AURKBCHEK1CDC7 | |
| SCHEMBL4039665 | 0.69 | DAO (0.47) | PARP1DAOAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930632-A | Tri-ring ubiquitin-specific protease 1 inhibitor, and preparation method, application and pharmaceutical composition thereof | 中国医学科学院药物研究所 | 2025-05-06 | — | — | CN | disclosed |
| CN-119930633-A | Pyrrolopyrrolidone ubiquitin specific protease 1 inhibitor, and preparation method, application and pharmaceutical composition thereof | 中国医学科学院药物研究所 | 2025-05-06 | — | — | CN | disclosed |