Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31492279 | 0.88 | CHRM2 (0.43) | CHRM4CYP2D6 | |
| SCHEMBL31492265 | 0.85 | CHRM4 (0.44) | CHRM4 | |
| SCHEMBL31492294 | 0.85 | CHRM2 (0.42) | CHRM4 | |
| SCHEMBL31492333 | 0.84 | GPR119 (0.40) | CHRM4CYP2D6CYP2C19 | |
| SCHEMBL31492336 | 0.84 | GPR119 (0.40) | CHRM4 | |
| SCHEMBL31492302 | 0.80 | CHRM2 (0.42) | CHRM4 | |
| SCHEMBL31492305 | 0.80 | CHRM2 (0.42) | CHRM4 | |
| SCHEMBL31492314 | 0.79 | CHRM2 (0.43) | CHRM4 | |
| SCHEMBL31492275 | 0.79 | CHRM4 (0.42) | CHRM4 | |
| SCHEMBL31492266 | 0.78 | CHRM4 (0.42) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092022-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092022-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | CHRM4, CHRM2, CHRM5 | CHRM4 1/4885CYP2D6 534/4885CYP3A4 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.