Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18299043 | 0.85 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1NOS3NOS1NOS2 | |
| SCHEMBL29739588 | 0.83 | KDM4E (0.46) | HSP90AA1HSP90AB1NOS3NOS1NOS2 | |
| SCHEMBL31492986 | 0.75 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1ALDH1A1LMNA | |
| SCHEMBL589612 | 0.74 | — | — | |
| SCHEMBL27269634 | 0.71 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1HSD17B10KDM4EATM | |
| SCHEMBL27029966 | 0.71 | KMT2A (0.44) | HSP90AA1HSP90AB1HSD17B10ALDH1A1KDM4E | |
| SCHEMBL15213218 | 0.69 | — | — | |
| SCHEMBL23344929 | 0.68 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1HSD17B10ALDH1A1TSHR | |
| SCHEMBL10399561 | 0.67 | — | — | |
| SCHEMBL5513652 | 0.67 | HSD17B10 (0.48) | HSD17B10ALDH1A1TSHRKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894879-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-25 | — | — | CN | disclosed |