⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3080756 | 1.00 | — | — | |
| SCHEMBL2801704 | 0.78 | — | — | |
| SCHEMBL3089364 | 0.78 | — | — | |
| SCHEMBL6111425 | 0.78 | — | — | |
| SCHEMBL6243651 | 0.78 | — | — | |
| SCHEMBL435717 | 0.78 | — | — | |
| SCHEMBL3089367 | 0.78 | — | — | |
| SCHEMBL1062864 | 0.78 | — | — | |
| SCHEMBL3051258 | 0.67 | — | — | |
| SCHEMBL17040309 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595243-B2 | Modulators of extracellular signal-regulated kinase | GEN1E LIFESCIENCES INC. (US) | 2026-04-07 | — | — | US | disclosed |
| US-20250353826-A1 | INHIBITORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE | GEN1E LIFESCIENCES INC (US) | 2025-11-20 | — | — | US | disclosed |
| US-12404259-B2 | Inhibitors of extracellular signal-regulated kinase | GEN1E LIFESCIENCES INC. (US) | 2025-09-02 | — | — | US | disclosed |
| US-20250136571-A1 | MODULATORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE | GEN1E LIFESCIENCES INC. | 2025-05-01 | — | — | US | disclosed |
| US-20250129038-A1 | INHIBITORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE | UNIVERSITY OF MARYLAND, BALTIMORE | 2025-04-24 | — | — | US | disclosed |
| WO-2025085745-A1 | MODULATORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE | GEN1E LIFESCIENCES INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085776-A1 | INHIBITORS OF EXTRACELLULAR SIGNAL-REGULATED KINASE | GEN1E LIFESCIENCES INC. (US) | 2025-04-24 | — | — | WO | disclosed |