Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 12/20 | 0.52 |
| ▸ | TGM1 | P22735 | 11/20 | 0.52 |
| ▸ | F13A1 | P00488 | 10/20 | 0.52 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27046568 | 1.00 | TGM2 (0.52) | TGM2TGM1F13A1TGM3SMN1; SMN2 | |
| SCHEMBL27046571 | 0.85 | TGM2 (0.50) | TGM2TGM1F13A1TGM3SMN1; SMN2 | |
| SCHEMBL10064223 | 0.79 | TGM2 (0.70) | TGM2TGM1F13A1TGM3SMN1; SMN2 | |
| SCHEMBL1872113 | 0.78 | TGM2 (0.67) | TGM2TGM1F13A1TGM3SMN1; SMN2 | |
| SCHEMBL1878082 | 0.77 | TGM2 (0.69) | TGM2TGM1F13A1TGM3SMN1; SMN2 | |
| SCHEMBL6237772 | 0.76 | MEN1 (0.61) | TGM2TGM1F13A1TGM3SMN1; SMN2 | |
| SCHEMBL12061638 | 0.76 | TGM2 (0.63) | TGM2TGM1F13A1TGM3SMN1; SMN2 | |
| SCHEMBL4814264 | 0.75 | MEN1 (0.76) | SMN1; SMN2CYP2C19KMT2AMEN1NPSR1 | |
| SCHEMBL3970912 | 0.75 | MEN1 (0.76) | SMN1; SMN2CYP2C19KMT2AMEN1NPSR1 | |
| SCHEMBL7393652 | 0.75 | MEN1 (0.76) | SMN1; SMN2CYP2C19KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251620-B1 | AMINO QUINAZOLINE DERIVATIVES AS P2X3 INHIBITORS | CHIESI FARM SPA (IT) | 2025-04-16 | — | — | EP | disclosed |