Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | DCK | P27707 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218763 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGDUSP2GAA | |
| SCHEMBL27218924 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGDUSP2GAA | |
| SCHEMBL27218882 | 0.86 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDUSP2GAA | |
| SCHEMBL27218767 | 0.85 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA | |
| SCHEMBL27218670 | 0.85 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA | |
| SCHEMBL31494328 | 0.85 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA | |
| SCHEMBL31494316 | 0.85 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA | |
| SCHEMBL27218700 | 0.85 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA | |
| SCHEMBL31494301 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA | |
| SCHEMBL27218696 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | claimed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | claimed |