Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218897 | 0.87 | MAPT (0.52) | TSHRLMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL27218793 | 0.87 | MAPT (0.52) | TSHRLMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL27218679 | 0.87 | MAPT (0.52) | TSHRLMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL27218943 | 0.87 | POLB (0.52) | TSHRLMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL27218646 | 0.84 | MAPT (0.48) | TSHRLMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL27218913 | 0.82 | LMNA (0.47) | TSHRLMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL27218916 | 0.81 | MAPT (0.50) | TSHRLMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL27218797 | 0.81 | MAPT (0.44) | TSHRLMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL27218716 | 0.80 | SMN1; SMN2 (0.56) | TSHRLMNAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL27218781 | 0.79 | NPC1 (0.54) | TSHRLMNAL3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | disclosed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | disclosed |