Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893257 | 0.81 | PBRM1 (0.50) | PBRM1ALDH1A1MAPK1AHRIDO1 | |
| SCHEMBL2404614 | 0.78 | LDHA (0.44) | ALDH1A1MAPK1IDO1RAB9ANPC1 | |
| SCHEMBL2406648 | 0.78 | NPC1 (0.43) | ALDH1A1MAPK1IDO1RAB9ANPC1 | |
| SCHEMBL28457966 | 0.77 | PBRM1 (0.47) | PBRM1ALDH1A1MAPK1AHRIDO1 | |
| SCHEMBL18015638 | 0.75 | PBRM1 (0.54) | PBRM1ALDH1A1MAPK1AHRIDO1 | |
| SCHEMBL18920526 | 0.75 | PBRM1 (0.59) | PBRM1ALDH1A1MAPK1AHRIDO1 | |
| SCHEMBL2404209 | 0.74 | CYP1A2 (0.46) | ALDH1A1MAPK1TSHRLMNAKDM4E | |
| SCHEMBL7351693 | 0.74 | CYP1A2 (0.56) | PBRM1ALDH1A1MAPK1AHRIDO1 | |
| SCHEMBL29882200 | 0.74 | CYP1A2 (0.56) | PBRM1ALDH1A1MAPK1AHRIDO1 | |
| SCHEMBL21390792 | 0.72 | MAPK1 (0.61) | ALDH1A1MAPK1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684263-A | Synthetic method of terpetinib and key intermediate thereof | 苏州莱安医药化学技术有限公司 | 2025-03-25 | — | — | CN | disclosed |