Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16174996 | 0.83 | TSHR (0.60) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL31346023 | 0.80 | TDP1 (0.53) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL31394919 | 0.80 | TSHR (0.43) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL30039907 | 0.79 | ALDH1A1 (0.40) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL2792876 | 0.77 | TSHR (0.53) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL364793 | 0.77 | ALDH1A1 (0.47) | TDP1TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL30038307 | 0.77 | TSHR (0.53) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL23302367 | 0.75 | ALDH1A1 (0.48) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL8162628 | 0.75 | TDP1 (0.60) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL29896834 | 0.75 | ALDH1A1 (0.48) | TDP1TSHRALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | disclosed |