Phosphoric Acid

Phosphoric Acid

SCHEMBL3149653

C=C(C)C(=O)OCC(O)O.O=P(O)(O)O

nearest known ligand 0.59

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.59
ALDH1A1 P00352 2/20 0.43
THRB P10828 1/20 0.41
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL631029 0.92 TSHR (0.68) TSHRALDH1A1THRBPOLBAPEX1
Phosphoric Acid SCHEMBL28502910 0.86 TSHR (0.62) TSHRALDH1A1THRBPGK1PGK2
SCHEMBL18279926 0.86 TSHR (0.61) TSHRALDH1A1THRBPOLBAPEX1
Phosphoric Acid SCHEMBL16620209 0.83 TSHR (0.53) TSHRALDH1A1THRB
Phosphoric Acid SCHEMBL4988141 0.83 TSHR (0.53) TSHRALDH1A1THRB
Succinic Acid SCHEMBL27828189 0.82 TSHR (0.57) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL8601929 0.82 TSHR (0.57) TSHRALDH1A1THRBPGK1PGK2
Phosphoric Acid SCHEMBL28146657 0.81 TSHR (0.48) TSHRALDH1A1THRBPOLBAPEX1
Methacrylic Acid SCHEMBL10702567 0.81 TSHR (0.55) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL6414251 0.80 TSHR (0.59) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7817337-B2 Screen for display and manufacturing method thereof SON CHANGMIN 2010-10-19 US claimed
US-20080123187-A1 Spam Short Message Blocking System Using A Call Back Short Message And A Method Thereof NURIVISION CO., LTD. (KR) 2008-05-29 US claimed
WO-2006073286-A1 SCREEN FOR DISPLAY AND MANUFACTURING METHOD THEREOF SON CHANGMIN (KR) 2006-07-13 WO claimed
CN-113754300-A Gradual thinning process of foldable glass 深圳市信濠光电科技股份有限公司 2021-12-07 CN disclosed
US-7817337-B2 Screen for display and manufacturing method thereof SON CHANGMIN 2010-10-19 US disclosed
US-20100051193-A1 PROJECTION SCREEN FABRICATION METHOD STEWART FILMSCREEN CORPORATION 2010-03-04 US disclosed
US-20080123187-A1 Spam Short Message Blocking System Using A Call Back Short Message And A Method Thereof NURIVISION CO., LTD. (KR) 2008-05-29 US disclosed
WO-2006073286-A1 SCREEN FOR DISPLAY AND MANUFACTURING METHOD THEREOF SON CHANGMIN (KR) 2006-07-13 WO disclosed