SCHEMBL31497338

CC(=O)N[C@H](C(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC1=O)[C@@H](C)O

nearest known ligand 0.50

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	9/20	0.50

▸	MC4R	P32245	1/20	0.41

▸	MC5R	P33032	1/20	0.41

▸	MC3R	P41968	1/20	0.41

▸	MC1R	Q01726	1/20	0.41

▸	SHH	Q15465	1/20	0.41

▸	TSLP	Q969D9	1/20	0.39

▸	ITGB3	P05106	1/20	0.38

▸	ITGA2B	P08514	1/20	0.38

▸	SLC6A3	Q01959	1/20	0.37

▸	SLC40A1	Q9NP59	1/20	0.37

▸	KLKB1	P03952	3/20	0.37

▸	PLAU	P00749	1/20	0.36

▸	KLK7	P49862	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31497370	0.96	KEAP1 (0.46)	KEAP1MC4RMC5RMC3RMC1R
SCHEMBL13857317	0.76	KEAP1 (0.54)	KEAP1TSLPITGB3ITGA2B
SCHEMBL13857319	0.75	KEAP1 (0.53)	KEAP1TSLPITGB3ITGA2B
SCHEMBL13857314	0.74	KEAP1 (0.55)	KEAP1TSLP
SCHEMBL13857318	0.73	KEAP1 (0.51)	KEAP1TSLPITGB3ITGA2B
SCHEMBL13857316	0.72	KEAP1 (0.55)	KEAP1TSLP
SCHEMBL13857313	0.72	KEAP1 (0.55)	KEAP1TSLP
SCHEMBL22342189	0.70	KEAP1 (0.60)	KEAP1TSLPPLAU
SCHEMBL31735712	0.70	MC3R (0.51)	KEAP1MC4RMC5RMC3RMC1R
SCHEMBL31735713	0.70	MC3R (0.51)	KEAP1MC4RMC5RMC3RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4545551-A1	PEPTIDE INHIBITOR AND USE THEREOF	Chengdu Brilliant Inspiration Biotherapeutics Co., Ltd (CN)	2025-04-30	—	—	EP	disclosed