Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16832074 | 0.82 | HCAR2 (0.34) | SMN1; SMN2MAPTALDH1A1CASP7CASP6 | |
| SCHEMBL31498921 | 0.81 | MAPT (0.38) | SMN1; SMN2MAPTALDH1A1CASP7CASP6 | |
| SCHEMBL1527741 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTALDH1A1CASP7CASP6 | |
| SCHEMBL30223609 | 0.75 | MAPT (0.48) | SMN1; SMN2MAPTALDH1A1CASP7CASP6 | |
| SCHEMBL9760940 | 0.74 | HTT (0.35) | SMN1; SMN2MAPTALDH1A1CASP7CASP6 | |
| SCHEMBL3575824 | 0.73 | ALDH1A1 (0.39) | SMN1; SMN2MAPTALDH1A1CASP7CASP6 | |
| SCHEMBL27848584 | 0.72 | MAPT (0.35) | SMN1; SMN2MAPTALDH1A1CASP7CASP6 | |
| SCHEMBL6363165 | 0.72 | HCAR2 (0.44) | SMN1; SMN2MAPTALDH1A1CASP7CASP6 | |
| SCHEMBL16832298 | 0.72 | MAPT (0.46) | SMN1; SMN2MAPTALDH1A1CASP7CASP6 | |
| SCHEMBL23580730 | 0.70 | DYRK1A (0.43) | SMN1; SMN2MAPTALDH1A1CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945571-B | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2025-02-25 | — | — | CN | disclosed |