Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.69 |
| ▸ | PARG | Q86W56 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.44 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499257 | 0.91 | BRD4 (0.61) | BRD4PARGGRIN1GRIN2BBRD9 | |
| SCHEMBL31499230 | 0.90 | BRD4 (0.72) | BRD4PARGGRIN1GRIN2BBRD2 | |
| SCHEMBL31499228 | 0.83 | BRD4 (0.61) | BRD4GRIN1GRIN2BBRD9 | |
| SCHEMBL31499250 | 0.80 | BRD4 (0.58) | BRD4GRIN1GRIN2BBRD9BRD2 | |
| SCHEMBL10084499 | 0.70 | TP53 (0.49) | PARGGRIN1GRIN2B | |
| SCHEMBL18538433 | 0.68 | BRD4 (0.55) | BRD4 | |
| SCHEMBL19925370 | 0.68 | BRD4 (0.72) | BRD4 | |
| SCHEMBL31499258 | 0.68 | BRD4 (0.46) | BRD4BRD9 | |
| SCHEMBL31499234 | 0.67 | PARG (0.50) | BRD4PARGGRIN1GRIN2B | |
| SCHEMBL31499256 | 0.66 | BRD4 (0.62) | BRD4PARGGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504726-A | BRD4 inhibitor and preparation method and application thereof | 四川大学华西医院 | 2025-02-25 | — | — | CN | disclosed |