Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499227 | 0.77 | ERN1 (0.44) | BRD4 | |
| SCHEMBL31499229 | 0.68 | BRD4 (0.69) | BRD4BRD9 | |
| SCHEMBL19869661 | 0.66 | BRD4 (0.75) | BRD4BRD9 | |
| SCHEMBL31499230 | 0.65 | BRD4 (0.72) | BRD4 | |
| SCHEMBL31499228 | 0.65 | BRD4 (0.61) | BRD4BRD9 | |
| SCHEMBL24556415 | 0.63 | BRD4 (0.69) | BRD4BRD9KDM4E | |
| SCHEMBL19869660 | 0.63 | BRD4 (0.69) | BRD4BRD9 | |
| SCHEMBL24556560 | 0.63 | BRD4 (0.54) | BRD4BRD9 | |
| SCHEMBL31499250 | 0.63 | BRD4 (0.58) | BRD4BRD9 | |
| SCHEMBL19869693 | 0.63 | BRD4 (0.64) | BRD4BRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504726-A | BRD4 inhibitor and preparation method and application thereof | 四川大学华西医院 | 2025-02-25 | — | — | CN | disclosed |