Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 3/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499244 | 0.83 | IDO1 (0.64) | BRD4KMT2AMEN1POLBIDO1 | |
| SCHEMBL17844281 | 0.80 | BRD4 (1.00) | BRD4EP300CREBBP | |
| SCHEMBL29920839 | 0.80 | MIF (0.61) | BRD4KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL17798015 | 0.80 | MIF (0.61) | BRD4KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL31499232 | 0.77 | BRD4 (0.64) | BRD4EP300CREBBP | |
| SCHEMBL31499235 | 0.68 | CREBBP (0.53) | BRD4CREBBP | |
| SCHEMBL31499237 | 0.67 | BRD4 (0.50) | BRD4ALDH1A1LMNAHTTEP300 | |
| SCHEMBL31499256 | 0.67 | BRD4 (0.62) | BRD4LMNA | |
| SCHEMBL31499245 | 0.67 | BRD4 (0.47) | BRD4EP300CREBBP | |
| SCHEMBL31499250 | 0.65 | BRD4 (0.58) | BRD4EP300CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504726-A | BRD4 inhibitor and preparation method and application thereof | 四川大学华西医院 | 2025-02-25 | — | — | CN | disclosed |