SCHEMBL31499348

SCHEMBL31499348

CC(C)(C)OC(=O)N1C(=O)C(c2ccccc2)c2ccc(F)cc21

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.40
RORC P51449 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ABCB1 P08183 1/20 0.37
CDK1 P06493 1/20 0.36
NR1H2 P55055 6/20 0.36
NR1H3 Q13133 4/20 0.36
RXRA P19793 2/20 0.36
KIF11 P52732 1/20 0.35
NR3C2 P08235 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
RIPK1 Q13546 1/20 0.35
HTR7 P34969 3/20 0.35
GPR119 Q8TDV5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31499325 0.91 BCHE (0.40) BCHERORCMEN1KMT2AABCB1
SCHEMBL31499335 0.87 BCHE (0.42) BCHERORCKMT2ACDK1RIPK1
SCHEMBL31499359 0.86 CDK1 (0.46) BCHERORCABCB1CDK1NR1H2
SCHEMBL31499320 0.86 BCHE (0.45) BCHERORCMEN1KMT2ACDK1
SCHEMBL18025768 0.85 BCHE (0.49) BCHERORCABCB1CDK1NR1H2
SCHEMBL31499363 0.85 BCHE (0.40) BCHEABCB1CDK1
SCHEMBL31499314 0.80 BCHE (0.41) BCHERORCMEN1KMT2AABCB1
SCHEMBL31499323 0.79 BCHE (0.40) BCHEMEN1KMT2AABCB1CDK1
SCHEMBL23959076 0.78 BCHE (0.40) BCHEMEN1KMT2ACDK1NR1H2
SCHEMBL23959420 0.78 BCHE (0.40) BCHEMEN1KMT2ACDK1NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954707-A Chiral 3, 3-disubstituted indolone compound and preparation method and application thereof 云南大学 2025-05-09 CN disclosed