Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959044 | 0.87 | CDK1 (0.46) | CDK1RORCBCHEBACE1NR1H2 | |
| SCHEMBL31499348 | 0.86 | BCHE (0.40) | CDK1RORCBCHEABCB1NR1H2 | |
| SCHEMBL18025768 | 0.85 | BCHE (0.49) | CDK1RORCBCHEBACE1ABCB1 | |
| SCHEMBL31499363 | 0.85 | BCHE (0.40) | CDK1BCHEABCB1EDNRAROCK2 | |
| SCHEMBL31499314 | 0.80 | BCHE (0.41) | CDK1RORCBCHEABCB1NR1H2 | |
| SCHEMBL31499322 | 0.80 | BCHE (0.39) | CDK1RORCBCHEABCB1NR1H2 | |
| SCHEMBL31499323 | 0.79 | BCHE (0.40) | CDK1BCHEABCB1 | |
| SCHEMBL31499325 | 0.79 | BCHE (0.40) | CDK1RORCBCHEABCB1NR1H2 | |
| SCHEMBL23959057 | 0.78 | CDK1 (0.46) | CDK1RORCBCHEBACE1NR1H2 | |
| SCHEMBL13536604 | 0.78 | ALDH1A1 (0.40) | CDK1BCHEABCB1NR1H2EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954707-A | Chiral 3, 3-disubstituted indolone compound and preparation method and application thereof | 云南大学 | 2025-05-09 | — | — | CN | disclosed |