SCHEMBL3149950

SCHEMBL3149950

C=CCOC(=O)CCCCCCCC(C(=O)OCC=C)C1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
EPHX2 P34913 1/20 0.42
ALDH1A1 P00352 3/20 0.37
GAA P10253 1/20 0.37
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
FAAH O00519 1/20 0.32
MGLL Q99685 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1897161 0.81 L3MBTL1 (0.39) TSHREPHX2ALDH1A1L3MBTL1LMNA
SCHEMBL1562364 0.76 FFAR4 (0.37) TSHREPHX2ALDH1A1
SCHEMBL28264667 0.76 L3MBTL1 (0.42) TSHREPHX2ALDH1A1L3MBTL1LMNA
SCHEMBL207971 0.74 FFAR4 (0.35) TSHRALDH1A1LMNA
SCHEMBL1019749 0.72 FFAR4 (0.41) TSHRALDH1A1LMNA
SCHEMBL28550279 0.71 TSHR (0.67) TSHREPHX2ALDH1A1GAATDP1
SCHEMBL29910307 0.71 TSHR (0.67) TSHREPHX2ALDH1A1GAATDP1
SCHEMBL5392962 0.70 TSHR (0.81) TSHREPHX2ALDH1A1GAATDP1
SCHEMBL11795597 0.70 TSHR (0.81) TSHREPHX2ALDH1A1GAATDP1
SCHEMBL10834721 0.70 TSHR (0.81) TSHREPHX2ALDH1A1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754801-B2 Latex emulsion containing one or more of the ultraviolet radiation protectors: zinc oxide, cerium oxide, transparent iron oxide and a hindered amine light stabilizer; paints and stains for wood COLUMBIA INSURANCE COMPANY (US) 2010-07-13 US disclosed
WO-2007102877-A2 TRANSLUCENT COATING COMPOSITIONS PROVIDING IMPROVED UV DEGRADATION RESISTANCE BENJAMIN MOORE & CO. (US) 2007-09-13 WO disclosed
US-20070155886-A1 Translucent coating compositions providing improved UV degradation resistance COLUMBIA INSURANCE COMPANY 2007-07-05 US disclosed