Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31384779 | 0.91 | WRN (0.54) | WRNACHEALDH1A1TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL31270598 | 0.90 | WRN (0.53) | WRNACHEALDH1A1TSHRKDM4E | |
| SCHEMBL25035228 | 0.87 | KDM4E (0.40) | TSHRKDM4EPOLBMEN1KMT2A | |
| SCHEMBL31499880 | 0.87 | WRN (0.48) | WRNACHEALDH1A1TSHRKDM4E | |
| SCHEMBL30037511 | 0.85 | WRN (0.48) | WRNALDH1A1TSHRKDM4EUSP2 | |
| SCHEMBL25036821 | 0.85 | WRN (0.48) | WRNALDH1A1TSHRKDM4EUSP2 | |
| SCHEMBL31394007 | 0.83 | WRN (0.52) | WRNACHEALDH1A1TSHRKDM4E | |
| SCHEMBL31387135 | 0.83 | WRN (0.46) | WRNALDH1A1TSHRMAPTMAPK9 | |
| Hydrochloric Acid SCHEMBL31387155 | 0.82 | WRN (0.46) | WRNALDH1A1TSHRMAPTMAPK9 | |
| SCHEMBL31499630 | 0.81 | WRN (0.49) | WRNACHEALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025087274-A1 | AZABICYCLO DERIVATIVE AND PREPARATION METHOD THEREFOR, AND USE | 浙江海正药业股份有限公司 | 2025-05-01 | — | — | WO | disclosed |
| CN-119899186-A | Azabicyclo derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-04-29 | — | — | CN | disclosed |