Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | WRN | Q14191 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25037077 | 0.94 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2ESR2NPC1 | |
| SCHEMBL31499661 | 0.90 | KMT2A (0.44) | MAPTALDH1A1SMN1; SMN2ESR2NPC1 | |
| SCHEMBL31394671 | 0.89 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2ESR2NPC1 | |
| SCHEMBL31499858 | 0.89 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2ESR2NPC1 | |
| SCHEMBL30037486 | 0.88 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2ESR2NPC1 | |
| SCHEMBL25035212 | 0.86 | WRN (0.49) | MAPTALDH1A1SMN1; SMN2ESR2WRN | |
| SCHEMBL30038096 | 0.86 | WRN (0.49) | MAPTALDH1A1SMN1; SMN2ESR2WRN | |
| SCHEMBL31500029 | 0.85 | WRN (0.47) | MAPTALDH1A1SMN1; SMN2ESR2NPC1 | |
| SCHEMBL25036710 | 0.85 | MAPT (0.47) | MAPTALDH1A1SMN1; SMN2ESR2NPC1 | |
| SCHEMBL31499616 | 0.85 | WRN (0.45) | MAPTALDH1A1SMN1; SMN2ESR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025087274-A1 | AZABICYCLO DERIVATIVE AND PREPARATION METHOD THEREFOR, AND USE | 浙江海正药业股份有限公司 | 2025-05-01 | — | — | WO | disclosed |
| CN-119899186-A | Azabicyclo derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-04-29 | — | — | CN | disclosed |