Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415028 | 0.80 | TSHR (0.45) | TSHRCYP3A4ALDH1A1MAPK1ALOX15 | |
| SCHEMBL10361848 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPK1CA12CA1CA2 | |
| SCHEMBL11226980 | 0.76 | TSHR (0.54) | TSHRCYP3A4ALDH1A1MAPK1ALOX15 | |
| SCHEMBL272102 | 0.76 | TSHR (0.54) | TSHRCYP3A4ALDH1A1MAPK1ALOX15 | |
| SCHEMBL10506973 | 0.73 | CYP3A4 (0.38) | TSHRCYP3A4ALDH1A1MAPK1ALOX15 | |
| SCHEMBL3791602 | 0.72 | TSHR (0.50) | TSHRCYP3A4ALDH1A1MAPK1ALOX15 | |
| SCHEMBL30827288 | 0.72 | TSHR (0.50) | TSHRCYP3A4ALDH1A1MAPK1ALOX15 | |
| SCHEMBL30599573 | 0.72 | ALDH1A1 (0.52) | TSHRCYP3A4ALDH1A1MAPK1ALOX15 | |
| SCHEMBL3628365 | 0.72 | ALDH1A1 (0.52) | TSHRCYP3A4ALDH1A1MAPK1ALOX15 | |
| SCHEMBL4149572 | 0.72 | MAPT (0.37) | ALDH1A1THRBGAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025087274-A1 | AZABICYCLO DERIVATIVE AND PREPARATION METHOD THEREFOR, AND USE | 浙江海正药业股份有限公司 | 2025-05-01 | — | — | WO | disclosed |