Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31500574 | 1.00 | WRN (0.55) | WRNALDH1A1SMN1; SMN2NPSR1POLB | |
| SCHEMBL25037158 | 0.98 | WRN (0.57) | WRNALDH1A1SMN1; SMN2NPSR1POLB | |
| SCHEMBL30038933 | 0.95 | WRN (0.54) | WRNALDH1A1SMN1; SMN2NPSR1POLB | |
| SCHEMBL30037701 | 0.92 | WRN (0.51) | WRNALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL25037307 | 0.92 | WRN (0.51) | WRNALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL25037157 | 0.91 | WRN (0.49) | WRNALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL30038247 | 0.91 | WRN (0.49) | WRNALDH1A1SMN1; SMN2NPSR1L3MBTL1 | |
| SCHEMBL31394893 | 0.90 | WRN (0.54) | WRNALDH1A1SMN1; SMN2NPSR1POLB | |
| SCHEMBL31214593 | 0.90 | WRN (0.54) | WRNALDH1A1SMN1; SMN2NPSR1POLB | |
| SCHEMBL31057847 | 0.90 | WRN (0.53) | WRNALDH1A1SMN1; SMN2NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025087274-A1 | AZABICYCLO DERIVATIVE AND PREPARATION METHOD THEREFOR, AND USE | 浙江海正药业股份有限公司 | 2025-05-01 | — | — | WO | disclosed |
| CN-119899186-A | Azabicyclo derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-04-29 | — | — | CN | disclosed |