Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376582 | 1.00 | CYP1A2 (0.42) | CYP1A2CYP2C19EGFRTDP1GLA | |
| SCHEMBL31436287 | 0.84 | TDP1 (0.45) | CYP1A2EGFRTDP1GLAALDH1A1 | |
| SCHEMBL31376537 | 0.84 | TDP1 (0.45) | CYP1A2EGFRTDP1GLAALDH1A1 | |
| SCHEMBL11584303 | 0.81 | CYP1A2 (0.42) | CYP1A2CYP2C19EGFRTDP1GLA | |
| SCHEMBL31376543 | 0.81 | MEN1 (0.49) | CYP1A2GLAALDH1A1LMNANPC1 | |
| SCHEMBL31436266 | 0.78 | CYP1A2 (0.56) | CYP1A2TDP1GLAALDH1A1LMNA | |
| SCHEMBL27810717 | 0.76 | CYP2D6 (0.37) | CYP1A2CYP2C19EGFRTDP1GLA | |
| SCHEMBL16865380 | 0.76 | KLK5 (0.46) | MAPTPPARA | |
| SCHEMBL16865378 | 0.76 | KLK5 (0.46) | MAPTPPARA | |
| SCHEMBL19167454 | 0.75 | CYP1A2 (0.44) | CYP1A2CYP2C19EGFRTDP1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250065315-A1 | IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES | Laboratory for Synthetic Chemistry and Chemical Biology Limited (CN) | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250065315-A1 | IRON COMPLEXES FOR ENANTIOSELECTIVE CIS DIHYDROXYLATION OF ALKENES | SQLE, NFE2L2, FECH | CYP1A2 18/4885CYP2C19 159/4885EGFR 1790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.