Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 7/20 | 0.39 |
| ▸ | DRD3 | P35462 | 7/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31501648 | 0.88 | MEN1 (0.44) | KCNH2MEN1KMT2ADRD2DRD3 | |
| SCHEMBL31501620 | 0.88 | KCNH2 (0.49) | KCNH2MEN1KMT2ADRD2DRD3 | |
| SCHEMBL31501622 | 0.83 | MEN1 (0.44) | KCNH2MEN1KMT2ADRD2DRD3 | |
| SCHEMBL31501657 | 0.79 | MEN1 (0.45) | KCNH2MEN1KMT2ADRD2DRD3 | |
| SCHEMBL31501673 | 0.79 | MEN1 (0.45) | KCNH2MEN1KMT2ADRD2DRD3 | |
| SCHEMBL31501666 | 0.79 | MEN1 (0.51) | KCNH2MEN1KMT2ADRD2DRD3 | |
| SCHEMBL31501723 | 0.79 | PIK3R1 (0.38) | MEN1PIK3R1PIK3CAMTOR | |
| SCHEMBL31501698 | 0.77 | ROCK2 (0.40) | PARP1PIK3R1PIK3CAMTOR | |
| SCHEMBL31501674 | 0.73 | MEN1 (0.39) | KCNH2MEN1KMT2ADRD2DRD3 | |
| SCHEMBL25278063 | 0.72 | MEN1 (0.48) | KCNH2MEN1KMT2ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | BALA THERAPEUTICS, INC. | 2025-02-27 | — | — | US | claimed |
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | BALA THERAPEUTICS, INC. | 2025-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | MLLT1, MEN1, BMI1 | KCNH2 4056/4885MEN1 2/4885KMT2A 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.